PATENTS AVAILABLE FOR LICENSING by NII New Delhi

PATENTS AVAILABLE FOR LICENSING

  
1) Indian patent 210537      Immunomodulatory compound for treating   cancer
                                         
Summary of Invention: A novel biologically active immunomodulatory compound  for treating cancer having the molecular formula C21H3O2, said compound having
improved bioactivity, bioavailability and solubility properties) 

2) Indian patent 197071  A process for isolation of a compound 1-(3,4-methylenedioxy- phenyl)-1e-tetradecene exhibiting immunomodulatory activity 
                                          
Summary of Invention: A process for isolation of a compound l-(3,4methylenedioxy

phenyl)-lE-tetradecene (mol formula C21H3O2) exhibiting
immunomodulatory activity, said process comprising: 

a. treating macerated and dried fruits of Piper longum with a solvent as hereindescribed, 
b. concentrating the extract below 50°C under reduced pressure, 
c. solvent fractionating the concentrate of step  

(b) using solvents such as a hydrocarbon, chlorinated hydrocarbon, ethyl acetate and water to obtain four fractions and identifying a biologically active fraction from the
said four fractions in a manner known per se, d. purifying the biologically active fraction by normal and reverse phase silica gel chromatography with solvent systems such as hereindescribed for elution, e. concentrating the fractions under reduced pressure and separating the compounds therein-, and f. screening the compounds separately for immunomodulatory activity and isolating the compound 1-(3,4methylenedioxy-phenyl)-lE-tetradecene (mol formula
C21H3O2) by conventional methods)


3) Indian patent 186770     A method of producing zpi protein 

Summary of Invention: A method production ZPI protein, said method comprising;
a. obtaining DMA sequence from ovarian tissue of Macdca radiota encoding for ZPI protein into a pCR script SK(+) vector by any known method; 
b. excising&ZPI transcript from soil vector and further making the same with suitable expression vector whereas detailed manner known per se; 
C. trahsfecting the-ZPI PQE-3O vector obtained above in a host cell such as SG13009(pREPOA), BL21(DE3) and gL2l
(plysS), and d. expressing ZPI protein from ransfected in'suitable nutrientndonitions by any khown.host claims and if desirecd adding any suitable adjuvant dilger its and
carriers. 

4) Indian patent 217322     A method for producing an inmuno-contraceptive vaccine 

Summary of Invention: The present invention relates to a method for producing an immuno-contraceptive vaccine comprising the steps of isolating and preparing amino
acid sequence comprising a peptide consisting of zona pellucida-1 (ZPl) shown in figure 3 mixing with the sequence with a pharmacologically-acceptable carrier, and optionally an adjuvant such as herein described in a ratio of 4:1. 

Contact Dr. Anil Kumar at anilk@nii.ac.in  or 011-26717106  before July 30, 2014